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Partial reversal of Rett Syndrome-like symptoms in MeCP2 mutant mice

Partial reversal of Rett Syndrome-like symptoms in MeCP2 mutant mice

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_fao_agris_US201301593123

Partial reversal of Rett Syndrome-like symptoms in MeCP2 mutant mice

About this item

Full title

Partial reversal of Rett Syndrome-like symptoms in MeCP2 mutant mice

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2009-02, Vol.106 (6), p.2029-2034

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

Rett Syndrome (RTT) is a severe form of X-linked mental retardation caused by mutations in the gene coding for methyl CpG-binding protein 2 (MECP2). Mice deficient in MeCP2 have a range of physiological and neurological abnormalities that mimic the human syndrome. Here we show that systemic treatment of MeCP2 mutant mice with an active peptide frag...

Alternative Titles

Full title

Partial reversal of Rett Syndrome-like symptoms in MeCP2 mutant mice

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_fao_agris_US201301593123

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_fao_agris_US201301593123

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.0812394106

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