Partial reversal of Rett Syndrome-like symptoms in MeCP2 mutant mice
Partial reversal of Rett Syndrome-like symptoms in MeCP2 mutant mice
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United States: National Academy of Sciences
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Language
English
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United States: National Academy of Sciences
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Rett Syndrome (RTT) is a severe form of X-linked mental retardation caused by mutations in the gene coding for methyl CpG-binding protein 2 (MECP2). Mice deficient in MeCP2 have a range of physiological and neurological abnormalities that mimic the human syndrome. Here we show that systemic treatment of MeCP2 mutant mice with an active peptide frag...
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Partial reversal of Rett Syndrome-like symptoms in MeCP2 mutant mice
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TN_cdi_fao_agris_US201301593123
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_fao_agris_US201301593123
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.0812394106