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Selective activation of FGFR4 by an FGF19 variant does not improve glucose metabolism in ob/ob mice

Selective activation of FGFR4 by an FGF19 variant does not improve glucose metabolism in ob/ob mice

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_fao_agris_US201301673385

Selective activation of FGFR4 by an FGF19 variant does not improve glucose metabolism in ob/ob mice

About this item

Full title

Selective activation of FGFR4 by an FGF19 variant does not improve glucose metabolism in ob/ob mice

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2009-08, Vol.106 (34), p.14379-14384

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

FGF19 is a hormone that regulates bile acid and glucose homeostasis. Progress has been made in identifying cofactors for receptor activation. However, several functions of FGF19 have not yet been fully defined, including the actions of FGF19 on target tissues, its FGF receptor specificity, and the contributions of other cofactors, such as heparin....

Alternative Titles

Full title

Selective activation of FGFR4 by an FGF19 variant does not improve glucose metabolism in ob/ob mice

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_fao_agris_US201301673385

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_fao_agris_US201301673385

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.0907812106

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