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In vivo translation rates can substantially delay the cotranslational folding of the Escherichia col...

In vivo translation rates can substantially delay the cotranslational folding of the Escherichia col...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_fao_agris_US201600136636

In vivo translation rates can substantially delay the cotranslational folding of the Escherichia coli cytosolic proteome

About this item

Full title

In vivo translation rates can substantially delay the cotranslational folding of the Escherichia coli cytosolic proteome

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2013-01, Vol.110 (2), p.E132-E140

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

A question of fundamental importance concerning protein folding in vivo is whether the kinetics of translation or the thermodynamics of the ribosome nascent chain (RNC) complex is the major determinant of cotranslational folding behavior. This is because translation rates can reduce the probability of cotranslational folding below that associated w...

Alternative Titles

Full title

In vivo translation rates can substantially delay the cotranslational folding of the Escherichia coli cytosolic proteome

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_fao_agris_US201600136636

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_fao_agris_US201600136636

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.1213624110

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