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Repurposing of bisphosphonates for the prevention and therapy of nonsmall cell lung and breast cance...

Repurposing of bisphosphonates for the prevention and therapy of nonsmall cell lung and breast cance...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_fao_agris_US201600139747

Repurposing of bisphosphonates for the prevention and therapy of nonsmall cell lung and breast cancer

About this item

Full title

Repurposing of bisphosphonates for the prevention and therapy of nonsmall cell lung and breast cancer

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2014-12, Vol.111 (50), p.17995-18000

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

Significance Small molecules to target oncogenic signaling cascades in cancer have achieved success in molecularly defined patient subsets. The path to approval is often protracted and plagued with failures. Repositioning Food and Drug Administration-approved drugs with known side effects has become a major focus. Bisphosphonates are a commonly pre...

Alternative Titles

Full title

Repurposing of bisphosphonates for the prevention and therapy of nonsmall cell lung and breast cancer

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_fao_agris_US201600139747

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_fao_agris_US201600139747

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.1421422111

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