structural analysis of shark IgNAR antibodies reveals evolutionary principles of immunoglobulins
structural analysis of shark IgNAR antibodies reveals evolutionary principles of immunoglobulins
About this item
Full title
Author / Creator
Publisher
United States: National Academy of Sciences
Journal title
Language
English
Formats
Publication information
Publisher
United States: National Academy of Sciences
Subjects
More information
Scope and Contents
Contents
Sharks and other cartilaginous fish are the phylogenetically oldest living organisms that rely on antibodies as part of their adaptive immune system. They produce the immunoglobulin new antigen receptor (IgNAR), a homodimeric heavy chain-only antibody, as a major part of their humoral adaptive immune response. Here, we report the atomic resolution...
Alternative Titles
Full title
structural analysis of shark IgNAR antibodies reveals evolutionary principles of immunoglobulins
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_fao_agris_US201600144055
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_fao_agris_US201600144055
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1321502111
