Targeting RPL39 and MLF2 reduces tumor initiation and metastasis in breast cancer by inhibiting nitr...
Targeting RPL39 and MLF2 reduces tumor initiation and metastasis in breast cancer by inhibiting nitric oxide synthase signaling
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Author / Creator
Dave, Bhuvanesh , Granados-Principal, Sergio , Zhu, Rui , Benz, Stephen , Rabizadeh, Shahrooz , Soon-Shiong, Patrick , Yu, Ke-Da , Shao, Zhimin , Li, Xiaoxian , Gilcrease, Michael , Lai, Zhao , Chen, Yidong , Huang, Tim H.-M. , Shen, Haifa , Liu, Xuewu , Ferrari, Mauro , Zhan, Ming , Wong, Stephen T. C. , Kumaraswami, Muthiah , Mittal, Vivek , Chen, Xi , Gross, Steven S. and Chang, Jenny C.
Publisher
United States: National Academy of Sciences
Journal title
Language
English
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Publication information
Publisher
United States: National Academy of Sciences
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Scope and Contents
Contents
We previously described a gene signature for breast cancer stem cells (BCSCs) derived from patient biopsies. Selective shRNA knockdown identified ribosomal protein L39 (RPL39) and myeloid leukemia factor 2 (MLF2) as the top candidates that affect BCSC self-renewal. Knockdown of RPL39 and MLF2 by specific siRNA nanoparticles in patient-derived and h...
Alternative Titles
Full title
Targeting RPL39 and MLF2 reduces tumor initiation and metastasis in breast cancer by inhibiting nitric oxide synthase signaling
Authors, Artists and Contributors
Author / Creator
Granados-Principal, Sergio
Zhu, Rui
Benz, Stephen
Rabizadeh, Shahrooz
Soon-Shiong, Patrick
Yu, Ke-Da
Shao, Zhimin
Li, Xiaoxian
Gilcrease, Michael
Lai, Zhao
Chen, Yidong
Huang, Tim H.-M.
Shen, Haifa
Liu, Xuewu
Ferrari, Mauro
Zhan, Ming
Wong, Stephen T. C.
Kumaraswami, Muthiah
Mittal, Vivek
Chen, Xi
Gross, Steven S.
Chang, Jenny C.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_fao_agris_US201600144300
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_fao_agris_US201600144300
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1320769111
