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p53 constrains progression to anaplastic thyroid carcinoma in a Braf-mutant mouse model of papillary...

p53 constrains progression to anaplastic thyroid carcinoma in a Braf-mutant mouse model of papillary...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_fao_agris_US201600144872

p53 constrains progression to anaplastic thyroid carcinoma in a Braf-mutant mouse model of papillary thyroid cancer

About this item

Full title

p53 constrains progression to anaplastic thyroid carcinoma in a Braf-mutant mouse model of papillary thyroid cancer

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2014-04, Vol.111 (16), p.E1600-E1609

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

Anaplastic thyroid carcinoma (ATC) has among the worst prognoses of any solid malignancy. The low incidence of the disease has in part precluded systematic clinical trials and tissue collection, and there has been little progress in developing effective therapies. v-raf murine sarcoma viral oncogene homolog B (BRAF) and tumor protein p53 (TP53) mut...

Alternative Titles

Full title

p53 constrains progression to anaplastic thyroid carcinoma in a Braf-mutant mouse model of papillary thyroid cancer

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_fao_agris_US201600144872

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_fao_agris_US201600144872

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.1404357111

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