Spatiotemporal expression and transcriptional perturbations by long noncoding RNAs in the mouse brai...
Spatiotemporal expression and transcriptional perturbations by long noncoding RNAs in the mouse brain
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Author / Creator
Goff, Loyal A. , Groff, Abigail F. , Sauvageau, Martin , Trayes-Gibson, Zachary , Sanchez-Gomez, Diana B. , Morse, Michael , Martin, Ryan D. , Elcavage, Lara E. , Liapis, Stephen C. , Gonzalez-Celeiro, Meryem , Plana, Olivia , Li, Eric , Gerhardinger, Chiara , Tomassy, Giulio S. , Arlotta, Paola and Rinn, John L.
Publisher
United States: National Academy of Sciences
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Language
English
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Publisher
United States: National Academy of Sciences
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Contents
Long noncoding RNAs (lncRNAs) have been implicated in numerous cellular processes including brain development. However, the in vivo expression dynamics and molecular pathways regulated by these loci are not well understood. Here, we leveraged a cohort of 13 lncRNA-null mutant mouse models to investigate the spatiotemporal expression of lncRNAs in t...
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Full title
Spatiotemporal expression and transcriptional perturbations by long noncoding RNAs in the mouse brain
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Record Identifier
TN_cdi_fao_agris_US201600145872
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_fao_agris_US201600145872
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1411263112