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Membranes serve as allosteric activators of phospholipase A₂, enabling it to extract, bind, and hydr...

Membranes serve as allosteric activators of phospholipase A₂, enabling it to extract, bind, and hydr...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_fao_agris_US201600149138

Membranes serve as allosteric activators of phospholipase A₂, enabling it to extract, bind, and hydrolyze phospholipid substrates

About this item

Full title

Membranes serve as allosteric activators of phospholipase A₂, enabling it to extract, bind, and hydrolyze phospholipid substrates

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2015-02, Vol.112 (6), p.E516-E525

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

Significance The catalytic mechanisms of interfacial enzymes acting directly on the interfacial surface of the membrane are notoriously difficult to study experimentally with X-ray crystallography and other biophysical methods. This scientific study is, to our knowledge, the first to highlight similarities and differences in the extraction and bind...

Alternative Titles

Full title

Membranes serve as allosteric activators of phospholipase A₂, enabling it to extract, bind, and hydrolyze phospholipid substrates

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_fao_agris_US201600149138

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_fao_agris_US201600149138

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.1424651112

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