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Expansion of human NK-22 cells with IL-7, IL-2, and IL-1β reveals intrinsic functional plasticity

Expansion of human NK-22 cells with IL-7, IL-2, and IL-1β reveals intrinsic functional plasticity

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_fao_agris_US201600189467

Expansion of human NK-22 cells with IL-7, IL-2, and IL-1β reveals intrinsic functional plasticity

About this item

Full title

Expansion of human NK-22 cells with IL-7, IL-2, and IL-1β reveals intrinsic functional plasticity

Publisher

National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2010, Vol.107 (24), p.10961-10966

Language

English

Formats

Publication information

Publisher

National Academy of Sciences

More information

Scope and Contents

Contents

Natural killer-22 (NK-22) cells are a human NK cell subset situated in mucosal-associated lymphoid tissues that specialize in IL-22 secretion in response to IL-23. Here we investigated the cytokine requirements for NK-22 cell expansion. IL-7 maintained the sur-vival of NK-22 cells and IL-22 production in response to IL-23 but was insufficient to in...

Alternative Titles

Full title

Expansion of human NK-22 cells with IL-7, IL-2, and IL-1β reveals intrinsic functional plasticity

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_fao_agris_US201600189467

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_fao_agris_US201600189467

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

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