Knockout of Sphingosine Kinase 1 Attenuates Renal Fibrosis in Unilateral Ureteral Obstruction Model
Knockout of Sphingosine Kinase 1 Attenuates Renal Fibrosis in Unilateral Ureteral Obstruction Model
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Basel, Switzerland: S. Karger AG
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English
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Basel, Switzerland: S. Karger AG
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Background: Sphingosine-1-phosphate (S1P) is a bioactive sphingolipid metabolite involved in various diseases. S1P also plays significant roles in the differentiation of fibroblasts into myofibroblasts, being implicated in fibrotic diseases. S1P is produced by the phosphorylation of sphingosine catalyzed by sphingosine kinases (SphK1 and SphK2). It...
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Knockout of Sphingosine Kinase 1 Attenuates Renal Fibrosis in Unilateral Ureteral Obstruction Model
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TN_cdi_gale_healthsolutions_A634316864
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_healthsolutions_A634316864
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ISSN
0250-8095,1421-9670
E-ISSN
1421-9670
DOI
10.1159/000502448
