Regulated Proteolytic Processing of Reelin through Interplay of Tissue Plasminogen Activator
Regulated Proteolytic Processing of Reelin through Interplay of Tissue Plasminogen Activator
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Public Library of Science
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Language
English
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Public Library of Science
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Contents
The extracellular signaling protein Reelin, indispensable for proper neuronal migration and cortical layering during development, is also expressed in the adult brain where it modulates synaptic functions. It has been shown that proteolytic processing of Reelin decreases its signaling activity and promotes Reelin aggregation in vitro, and that prot...
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Full title
Regulated Proteolytic Processing of Reelin through Interplay of Tissue Plasminogen Activator
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TN_cdi_gale_incontextgauss_ISR_A498259524
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_incontextgauss_ISR_A498259524
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0047793
