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Rb deletion in mouse mammary progenitors induces luminal-B or basal-like/EMT tumor subtypes dependin...

Rb deletion in mouse mammary progenitors induces luminal-B or basal-like/EMT tumor subtypes dependin...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracacademiconefile_A241883277

Rb deletion in mouse mammary progenitors induces luminal-B or basal-like/EMT tumor subtypes depending on p53 status

About this item

Full title

Rb deletion in mouse mammary progenitors induces luminal-B or basal-like/EMT tumor subtypes depending on p53 status

Publisher

American Society for Clinical Investigation

Journal title

The Journal of clinical investigation, 2010-09, Vol.120 (9), p.3296

Language

English

Formats

Publication information

Publisher

American Society for Clinical Investigation

More information

Scope and Contents

Contents

Breast cancer is a highly heterogeneous disease, with several different subtypes being characterized by distinct histology, gene expression patterns, and genetic alterations. The tumor suppressor gene retinoblastoma 1 (RB1) is frequently lost in both luminal-B and triple-negative tumor (TNT; i.e., estrogen receptor-, progesterone receptor-, and hum...

Alternative Titles

Full title

Rb deletion in mouse mammary progenitors induces luminal-B or basal-like/EMT tumor subtypes depending on p53 status

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_gale_infotracacademiconefile_A241883277

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracacademiconefile_A241883277

Other Identifiers

ISSN

0021-9738

DOI

10.1172/JCI41490.

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