Sca/e: a chemical approach for fluorescence imaging and reconstruction of transparent mouse brain
Sca/e: a chemical approach for fluorescence imaging and reconstruction of transparent mouse brain
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Nature Publishing Group
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English
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Nature Publishing Group
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Optical methods for viewing neuronal populations and projections in the intact mammalian brain are needed, but light scattering prevents imaging deep into brain structures. We imaged fixed brain tissue using Sca/e, an aqueous reagent that renders biological samples optically transparent but completely preserves fluorescent signals in the clarified...
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Sca/e: a chemical approach for fluorescence imaging and reconstruction of transparent mouse brain
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TN_cdi_gale_infotracacademiconefile_A272078537
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracacademiconefile_A272078537
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ISSN
1097-6256
DOI
10.1038/nn.2928
