The microRNA miR-155 controls [CD8.sup.+] T cell responses by regulating interferon signaling
The microRNA miR-155 controls [CD8.sup.+] T cell responses by regulating interferon signaling
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Nature Publishing Group
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English
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Nature Publishing Group
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We found upregulation of expression of the microRNA miR-155 in primary effector and effector memory [CD8.sup.+] T cells, but low miR-155 expression in naive and central memory cells. Antiviral [CD8.sup.+] T cell responses and viral clearance were impaired in miR-155-deficient mice, and this defect was intrinsic to [CD8.sup.+] T cells, as miR-155-de...
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The microRNA miR-155 controls [CD8.sup.+] T cell responses by regulating interferon signaling
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TN_cdi_gale_infotracacademiconefile_A332656065
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracacademiconefile_A332656065
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ISSN
1529-2908
DOI
10.1038/ni.2576
