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The microRNA miR-155 controls [CD8.sup.+] T cell responses by regulating interferon signaling

The microRNA miR-155 controls [CD8.sup.+] T cell responses by regulating interferon signaling

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracacademiconefile_A332656065

The microRNA miR-155 controls [CD8.sup.+] T cell responses by regulating interferon signaling

About this item

Full title

The microRNA miR-155 controls [CD8.sup.+] T cell responses by regulating interferon signaling

Publisher

Nature Publishing Group

Journal title

Nature immunology, 2013-06, Vol.14 (6), p.593

Language

English

Formats

Publication information

Publisher

Nature Publishing Group

More information

Scope and Contents

Contents

We found upregulation of expression of the microRNA miR-155 in primary effector and effector memory [CD8.sup.+] T cells, but low miR-155 expression in naive and central memory cells. Antiviral [CD8.sup.+] T cell responses and viral clearance were impaired in miR-155-deficient mice, and this defect was intrinsic to [CD8.sup.+] T cells, as miR-155-de...

Alternative Titles

Full title

The microRNA miR-155 controls [CD8.sup.+] T cell responses by regulating interferon signaling

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_gale_infotracacademiconefile_A332656065

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracacademiconefile_A332656065

Other Identifiers

ISSN

1529-2908

DOI

10.1038/ni.2576

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