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Anti-CD20 single chain variable antibody fragment–apolipoprotein A-I chimera containing nanodisks pr...

Anti-CD20 single chain variable antibody fragment–apolipoprotein A-I chimera containing nanodisks pr...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracacademiconefile_A426258163

Anti-CD20 single chain variable antibody fragment–apolipoprotein A-I chimera containing nanodisks promote targeted bioactive agent delivery to CD20-positive lymphomas

About this item

Full title

Anti-CD20 single chain variable antibody fragment–apolipoprotein A-I chimera containing nanodisks promote targeted bioactive agent delivery to CD20-positive lymphomas

Publisher

Canada: NRC Research Press

Journal title

Biochemistry and cell biology, 2015-08, Vol.93 (4), p.343-350

Language

English

Formats

Publication information

Publisher

Canada: NRC Research Press

More information

Scope and Contents

Contents

A fusion protein comprising an α-CD20 single chain variable fragment (scFv) antibody, a spacer peptide, and human apolipoprotein (apo) A-I was constructed and expressed in Escherichia coli. The lipid interaction properties intrinsic to apoA-I as well as the antigen recognition properties of the scFv were retained by the chimera. scFv•apoA-I was for...

Alternative Titles

Full title

Anti-CD20 single chain variable antibody fragment–apolipoprotein A-I chimera containing nanodisks promote targeted bioactive agent delivery to CD20-positive lymphomas

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_gale_infotracacademiconefile_A426258163

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracacademiconefile_A426258163

Other Identifiers

ISSN

0829-8211

E-ISSN

1208-6002

DOI

10.1139/bcb-2015-0009

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