IL-34 mediates acute kidney injury and worsens subsequent chronic kidney disease
IL-34 mediates acute kidney injury and worsens subsequent chronic kidney disease
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Publisher
American Society for Clinical Investigation
Journal title
Language
English
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Publisher
American Society for Clinical Investigation
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Scope and Contents
Contents
Macrophages (Mo) are integral in ischemia/reperfusion injury-incited (I/R-incited) acute kidney injury (AKI) that leads to fibrosis and chronic kidney disease (CKD). IL-34 and CSF-1 share a receptor (c-FMS), and both cytokines mediate Mo survival and proliferation but also have distinct features. CSF-1 is central to kidney repair and destruction. W...
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Full title
IL-34 mediates acute kidney injury and worsens subsequent chronic kidney disease
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TN_cdi_gale_infotracacademiconefile_A428177077
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracacademiconefile_A428177077
Other Identifiers
ISSN
0021-9738
DOI
10.1172/JCI81166.
