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Improved Learning and Memory in Aged Mice Deficient in Amyloid [beta]-Degrading Neutral Endopeptidas...

Improved Learning and Memory in Aged Mice Deficient in Amyloid [beta]-Degrading Neutral Endopeptidas...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracacademiconefile_A473399036

Improved Learning and Memory in Aged Mice Deficient in Amyloid [beta]-Degrading Neutral Endopeptidase

About this item

Full title

Improved Learning and Memory in Aged Mice Deficient in Amyloid [beta]-Degrading Neutral Endopeptidase

Publisher

Public Library of Science

Journal title

PloS one, 2009-02, Vol.4 (2), p.e4590

Language

English

Formats

Publication information

Publisher

Public Library of Science

More information

Scope and Contents

Contents

Background Neutral endopeptidase, also known as neprilysin and abbreviated NEP, is considered to be one of the key enzymes in initial human amyloid-[beta] (A[beta]) degradation. The aim of our study was to explore the impact of NEP deficiency on the initial development of dementia-like symptoms in mice. Methodology/Principal Findings We found that...

Alternative Titles

Full title

Improved Learning and Memory in Aged Mice Deficient in Amyloid [beta]-Degrading Neutral Endopeptidase

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_gale_infotracacademiconefile_A473399036

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracacademiconefile_A473399036

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0004590

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