Deletion of HP1[gamma] in cardiac myocytes affects H4K20me3 levels but does not impact cardiac growt...
Deletion of HP1[gamma] in cardiac myocytes affects H4K20me3 levels but does not impact cardiac growth
About this item
Full title
Author / Creator
Publisher
BioMed Central Ltd
Journal title
Language
English
Formats
Publication information
Publisher
BioMed Central Ltd
Subjects
More information
Scope and Contents
Contents
Heterochromatin, which is formed when tri-methyl lysine 9 of histone H3 (H3K9me3) is bound by heterochromatin 1 proteins (HP1s), plays an important role in differentiation and senescence by silencing cell cycle genes. Cardiac myocytes (CMs) accumulate heterochromatin during differentiation and demethylation of H3K9me3 inhibits cell cycle gene silen...
Alternative Titles
Full title
Deletion of HP1[gamma] in cardiac myocytes affects H4K20me3 levels but does not impact cardiac growth
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_gale_infotracacademiconefile_A546834955
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracacademiconefile_A546834955
Other Identifiers
ISSN
1756-8935
E-ISSN
1756-8935
DOI
10.1186/s13072-018-0187-z
