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Wdr62 is involved in meiotic initiation via activating JNK signaling and associated with POI in huma...

Wdr62 is involved in meiotic initiation via activating JNK signaling and associated with POI in huma...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracacademiconefile_A557859968

Wdr62 is involved in meiotic initiation via activating JNK signaling and associated with POI in humans

About this item

Full title

Wdr62 is involved in meiotic initiation via activating JNK signaling and associated with POI in humans

Publisher

Public Library of Science

Journal title

PLoS genetics, 2018-08, Vol.14 (8)

Language

English

Formats

Publication information

Publisher

Public Library of Science

More information

Scope and Contents

Contents

Meiosis is a germ cell-specific division that is indispensable for the generation of haploid gametes. However, the regulatory mechanisms of meiotic initiation remain elusive. Here, we report that the Wdr62 (WD40-repeat protein 62) is involved in meiotic initiation as a permissive factor rather than an instructive factor. Knock-out of this gene in a...

Alternative Titles

Full title

Wdr62 is involved in meiotic initiation via activating JNK signaling and associated with POI in humans

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_gale_infotracacademiconefile_A557859968

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracacademiconefile_A557859968

Other Identifiers

ISSN

1553-7390

DOI

10.1371/journal.pgen.1007463

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