Wdr62 is involved in meiotic initiation via activating JNK signaling and associated with POI in huma...
Wdr62 is involved in meiotic initiation via activating JNK signaling and associated with POI in humans
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Zhou, Yang , Qin, Yan , Qin, Yingying , Xu, Binyang , Guo, Ting , Ke, Hanni , Chen, Min , Zhang, Lianjun , Han, Feng , Li, Yaqiong , Behrens, Axel , Wang, Yaqing , Xu, Zhiheng , Chen, Zi-Jiang and Gao, Fei
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Public Library of Science
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English
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Public Library of Science
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Meiosis is a germ cell-specific division that is indispensable for the generation of haploid gametes. However, the regulatory mechanisms of meiotic initiation remain elusive. Here, we report that the Wdr62 (WD40-repeat protein 62) is involved in meiotic initiation as a permissive factor rather than an instructive factor. Knock-out of this gene in a...
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Wdr62 is involved in meiotic initiation via activating JNK signaling and associated with POI in humans
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TN_cdi_gale_infotracacademiconefile_A557859968
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracacademiconefile_A557859968
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ISSN
1553-7390
DOI
10.1371/journal.pgen.1007463
