Absence of PD-L1 expression on tumor cells in the context of an activated immune infiltrate may indi...
Absence of PD-L1 expression on tumor cells in the context of an activated immune infiltrate may indicate impaired IFN[gamma] signaling in non-small cell lung cancer
About this item
Full title
Author / Creator
Theelen, Willemijn S. M. E , Kuilman, Thomas , Schulze, Katja , Zou, Wei , Krijgsman, Oscar , Peters, Dennis D. G. C , Cornelissen, Sten , Monkhorst, Kim , Sarma, Pranamee , Sumiyoshi, Teiko , Amler, Lukas C , Willems, Stefan M , Blaauwgeers, Johannes L. G , van Noesel, Carel J. M , Peeper, Daniel S , van den Heuvel, Michel M and Kowanetz, Marcin
Publisher
Public Library of Science
Journal title
Language
English
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Publication information
Publisher
Public Library of Science
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Scope and Contents
Contents
Background In non-small cell lung cancer (NSCLC), PD-L1 expression on either tumor cells (TC) or both TC and tumor-infiltrating immune cells (IC) is currently the most used biomarker in cancer immunotherapy. However, the mechanisms involved in PD-L1 regulation are not fully understood. To provide better insight in these mechanisms, a multiangular a...
Alternative Titles
Full title
Absence of PD-L1 expression on tumor cells in the context of an activated immune infiltrate may indicate impaired IFN[gamma] signaling in non-small cell lung cancer
Authors, Artists and Contributors
Author / Creator
Kuilman, Thomas
Schulze, Katja
Zou, Wei
Krijgsman, Oscar
Peters, Dennis D. G. C
Cornelissen, Sten
Monkhorst, Kim
Sarma, Pranamee
Sumiyoshi, Teiko
Amler, Lukas C
Willems, Stefan M
Blaauwgeers, Johannes L. G
van Noesel, Carel J. M
Peeper, Daniel S
van den Heuvel, Michel M
Kowanetz, Marcin
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_gale_infotracacademiconefile_A586555305
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracacademiconefile_A586555305
Other Identifiers
ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0216864
