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Absence of PD-L1 expression on tumor cells in the context of an activated immune infiltrate may indi...

Absence of PD-L1 expression on tumor cells in the context of an activated immune infiltrate may indi...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracacademiconefile_A586555305

Absence of PD-L1 expression on tumor cells in the context of an activated immune infiltrate may indicate impaired IFN[gamma] signaling in non-small cell lung cancer

About this item

Full title

Absence of PD-L1 expression on tumor cells in the context of an activated immune infiltrate may indicate impaired IFN[gamma] signaling in non-small cell lung cancer

Publisher

Public Library of Science

Journal title

PloS one, 2019-05, Vol.14 (5), p.e0216864

Language

English

Formats

Publication information

Publisher

Public Library of Science

More information

Scope and Contents

Contents

Background In non-small cell lung cancer (NSCLC), PD-L1 expression on either tumor cells (TC) or both TC and tumor-infiltrating immune cells (IC) is currently the most used biomarker in cancer immunotherapy. However, the mechanisms involved in PD-L1 regulation are not fully understood. To provide better insight in these mechanisms, a multiangular a...

Alternative Titles

Full title

Absence of PD-L1 expression on tumor cells in the context of an activated immune infiltrate may indicate impaired IFN[gamma] signaling in non-small cell lung cancer

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_gale_infotracacademiconefile_A586555305

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracacademiconefile_A586555305

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0216864

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