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Reversal of P-glycoprotein-mediated multidrug resistance by novel curcumin analogues in paclitaxel-r...

Reversal of P-glycoprotein-mediated multidrug resistance by novel curcumin analogues in paclitaxel-r...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracacademiconefile_A632724189

Reversal of P-glycoprotein-mediated multidrug resistance by novel curcumin analogues in paclitaxel-resistant human breast cancer cells

About this item

Full title

Reversal of P-glycoprotein-mediated multidrug resistance by novel curcumin analogues in paclitaxel-resistant human breast cancer cells

Publisher

1840 Woodward Drive, Suite 1, Ottawa, ON K2C 0P7: NRC Research Press

Journal title

Biochemistry and cell biology, 2020-07, Vol.98 (4), p.484-491

Language

English

Formats

Publication information

Publisher

1840 Woodward Drive, Suite 1, Ottawa, ON K2C 0P7: NRC Research Press

More information

Scope and Contents

Contents

Multidrug resistance (MDR) is a major obstacle for successful cancer chemotherapy, and the main cause of MDR has been attributed to overexpression of P-glycoprotein (P-gp). In this present study, four P-gp modulators (E,E)-4,6-bis(styryl)-2-(substituted amino)-pyrimidines were evaluated for their activity in a breast cancer cell line overexpressing...

Alternative Titles

Full title

Reversal of P-glycoprotein-mediated multidrug resistance by novel curcumin analogues in paclitaxel-resistant human breast cancer cells

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_gale_infotracacademiconefile_A632724189

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracacademiconefile_A632724189

Other Identifiers

ISSN

0829-8211

E-ISSN

1208-6002

DOI

10.1139/bcb-2019-0377

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