Reversal of P-glycoprotein-mediated multidrug resistance by novel curcumin analogues in paclitaxel-r...
Reversal of P-glycoprotein-mediated multidrug resistance by novel curcumin analogues in paclitaxel-resistant human breast cancer cells
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Full title
Author / Creator
Gao, Lei , Zhao, Peiran , Li, Yang , Yang, Dawei , Hu, Ping , Li, Lianzhi , Cheng, Yufeng and Yao, Hengchen
Publisher
1840 Woodward Drive, Suite 1, Ottawa, ON K2C 0P7: NRC Research Press
Journal title
Language
English
Formats
Publication information
Publisher
1840 Woodward Drive, Suite 1, Ottawa, ON K2C 0P7: NRC Research Press
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Scope and Contents
Contents
Multidrug resistance (MDR) is a major obstacle for successful cancer chemotherapy, and the main cause of MDR has been attributed to overexpression of P-glycoprotein (P-gp). In this present study, four P-gp modulators (E,E)-4,6-bis(styryl)-2-(substituted amino)-pyrimidines were evaluated for their activity in a breast cancer cell line overexpressing...
Alternative Titles
Full title
Reversal of P-glycoprotein-mediated multidrug resistance by novel curcumin analogues in paclitaxel-resistant human breast cancer cells
Authors, Artists and Contributors
Author / Creator
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Primary Identifiers
Record Identifier
TN_cdi_gale_infotracacademiconefile_A632724189
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracacademiconefile_A632724189
Other Identifiers
ISSN
0829-8211
E-ISSN
1208-6002
DOI
10.1139/bcb-2019-0377