Chemogenetic attenuation of neuronal activity in the entorhinal cortex reduces A[beta] and tau patho...
Chemogenetic attenuation of neuronal activity in the entorhinal cortex reduces A[beta] and tau pathology in the hippocampus
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Public Library of Science
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English
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Public Library of Science
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High levels of the amyloid-beta (A[beta]) peptide have been shown to disrupt neuronal function and induce hyperexcitability, but it is unclear what effects A[beta]-associated hyperexcitability may have on tauopathy pathogenesis or propagation in vivo. Using a novel transgenic mouse line to model the impact of human APP (hAPP)/A[beta] accumulation o...
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Chemogenetic attenuation of neuronal activity in the entorhinal cortex reduces A[beta] and tau pathology in the hippocampus
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TN_cdi_gale_infotracacademiconefile_A634243291
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracacademiconefile_A634243291
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ISSN
1544-9173
DOI
10.1371/journal.pbio.3000851
