Identifying treatment options for BRAF.sup.V600 wild-type metastatic melanoma: A SU2C/MRA genomics-e...
Identifying treatment options for BRAF.sup.V600 wild-type metastatic melanoma: A SU2C/MRA genomics-enabled clinical trial
About this item
Full title
Author / Creator
LoRusso, Patricia M , Sekulic, Aleksandar , Sosman, Jeffrey A , Liang, Winnie S , Carpten, John , Craig, David W , Solit, David B , Bryce, Alan H , Kiefer, Jeffrey A , Aldrich, Jessica , Nasser, Sara , Halperin, Rebecca , Byron, Sara A , Pilat, Mary Jo , Boerner, Scott A , Durecki, Diane , Hendricks, William P. D , Enriquez, Daniel , Izatt, Tyler , Keats, Jonathan , Legendre, Christophe , Markovic, Svetomir N , Weise, Amy , Naveed, Fatima , Schmidt, Jessica , Basu, Gargi D , Sekar, Shobana , Adkins, Jonathan , Tassone, Erica , Sivaprakasam, Karthigayini , Zismann, Victoria , Calvert, Valerie S , Petricoin, Emanuel F , Fecher, Leslie Anne , Lao, Christopher , Eder, J. Paul , Vogelzang, Nicholas J , Perlmutter, Jane , Gorman, Mark , Manica, Barbara , Fox, Lisa , Schork, Nicholas , Zelterman, Daniel , DeVeaux, Michelle , Joseph, Richard W , Cowey, C. Lance and Trent, Jeffrey M
Publisher
Public Library of Science
Journal title
Language
English
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Publication information
Publisher
Public Library of Science
Subjects
More information
Scope and Contents
Contents
Although combination BRAF and MEK inhibitors are highly effective for the 40-50% of cutaneous metastatic melanomas harboring BRAF.sup.V600 mutations, targeted agents have been ineffective for BRAF.sup.V600 wild-type (wt) metastatic melanomas. The SU2C Genomics-Enabled Medicine for Melanoma Trial utilized a Simon two-stage optimal design to assess w...
Alternative Titles
Full title
Identifying treatment options for BRAF.sup.V600 wild-type metastatic melanoma: A SU2C/MRA genomics-enabled clinical trial
Authors, Artists and Contributors
Author / Creator
Sekulic, Aleksandar
Sosman, Jeffrey A
Liang, Winnie S
Carpten, John
Craig, David W
Solit, David B
Bryce, Alan H
Kiefer, Jeffrey A
Aldrich, Jessica
Nasser, Sara
Halperin, Rebecca
Byron, Sara A
Pilat, Mary Jo
Boerner, Scott A
Durecki, Diane
Hendricks, William P. D
Enriquez, Daniel
Izatt, Tyler
Keats, Jonathan
Legendre, Christophe
Markovic, Svetomir N
Weise, Amy
Naveed, Fatima
Schmidt, Jessica
Basu, Gargi D
Sekar, Shobana
Adkins, Jonathan
Tassone, Erica
Sivaprakasam, Karthigayini
Zismann, Victoria
Calvert, Valerie S
Petricoin, Emanuel F
Fecher, Leslie Anne
Lao, Christopher
Eder, J. Paul
Vogelzang, Nicholas J
Perlmutter, Jane
Gorman, Mark
Manica, Barbara
Fox, Lisa
Schork, Nicholas
Zelterman, Daniel
DeVeaux, Michelle
Joseph, Richard W
Cowey, C. Lance
Trent, Jeffrey M
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_gale_infotracacademiconefile_A657706393
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracacademiconefile_A657706393
Other Identifiers
ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0248097
