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Aη-[alpha] and Aη-[beta] peptides impair LTP ex vivo within the low nanomolar range and impact neu...

Aη-[alpha] and Aη-[beta] peptides impair LTP ex vivo within the low nanomolar range and impact neu...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracacademiconefile_A672329001

Aη-[alpha] and Aη-[beta] peptides impair LTP ex vivo within the low nanomolar range and impact neuronal activity in vivo

About this item

Full title

Aη-[alpha] and Aη-[beta] peptides impair LTP ex vivo within the low nanomolar range and impact neuronal activity in vivo

Publisher

BioMed Central Ltd

Journal title

Alzheimer's research & therapy, 2021-07, Vol.13 (1)

Language

English

Formats

Publication information

Publisher

BioMed Central Ltd

More information

Scope and Contents

Contents

Background Amyloid precursor protein (APP) processing is central to Alzheimer's disease (AD) etiology. As early cognitive alterations in AD are strongly correlated to abnormal information processing due to increasing synaptic impairment, it is crucial to characterize how peptides generated through APP cleavage modulate synapse function. We previous...

Alternative Titles

Full title

Aη-[alpha] and Aη-[beta] peptides impair LTP ex vivo within the low nanomolar range and impact neuronal activity in vivo

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_gale_infotracacademiconefile_A672329001

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracacademiconefile_A672329001

Other Identifiers

ISSN

1758-9193

E-ISSN

1758-9193

DOI

10.1186/s13195-021-00860-1

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