Aη-[alpha] and Aη-[beta] peptides impair LTP ex vivo within the low nanomolar range and impact neu...
Aη-[alpha] and Aη-[beta] peptides impair LTP ex vivo within the low nanomolar range and impact neuronal activity in vivo
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BioMed Central Ltd
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English
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BioMed Central Ltd
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Background Amyloid precursor protein (APP) processing is central to Alzheimer's disease (AD) etiology. As early cognitive alterations in AD are strongly correlated to abnormal information processing due to increasing synaptic impairment, it is crucial to characterize how peptides generated through APP cleavage modulate synapse function. We previous...
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Aη-[alpha] and Aη-[beta] peptides impair LTP ex vivo within the low nanomolar range and impact neuronal activity in vivo
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TN_cdi_gale_infotracacademiconefile_A672329001
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracacademiconefile_A672329001
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1758-9193
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1758-9193
DOI
10.1186/s13195-021-00860-1