Enhancing VTA Ca.sub.v1.3 L-type Ca.sup.2+ channel activity promotes cocaine and mood-related behavi...
Enhancing VTA Ca.sub.v1.3 L-type Ca.sup.2+ channel activity promotes cocaine and mood-related behaviors via overlapping AMPA receptor mechanisms in the nucleus accumbens
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Martínez-Rivera, A , Hao, J , Tropea, T F , Giordano, T P , Kosovsky, M , Rice, R C and Lee, A
Publisher
Nature Publishing Group
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Language
English
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Nature Publishing Group
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Genetic factors significantly influence susceptibility for substance abuse and mood disorders. Rodent studies have begun to elucidate a role of Ca.sub.v1.3 L-type Ca.sup.2+ channels in neuropsychiatric-related behaviors, such as addictive and depressive-like behaviors. Human studies have also linked the CACNA1D gene, which codes for the Ca.sub.v1.3...
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Full title
Enhancing VTA Ca.sub.v1.3 L-type Ca.sup.2+ channel activity promotes cocaine and mood-related behaviors via overlapping AMPA receptor mechanisms in the nucleus accumbens
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TN_cdi_gale_infotracacademiconefile_A689287042
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracacademiconefile_A689287042
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ISSN
1359-4184
DOI
10.1038/mp.2017.9