Sex and Age Influence on Association of ICYP450/I Polymorphism with Midazolam Levels in Critically I...
Sex and Age Influence on Association of ICYP450/I Polymorphism with Midazolam Levels in Critically Ill Children
About this item
Full title
Author / Creator
Publisher
MDPI AG
Journal title
Language
English
Formats
Publication information
Publisher
MDPI AG
Subjects
More information
Scope and Contents
Contents
Midazolam is a drug that is metabolized by cytochrome P450 (CYP450) enzymes, particularly CYP3A4 and CYP3A5. The present study aimed to determine the sex and age influence on association of CYP450 polymorphism with midazolam levels in critically ill children. Seventy-two DNA samples were genotyped by real-time PCR. Children ≤ five years of age who...
Alternative Titles
Full title
Sex and Age Influence on Association of ICYP450/I Polymorphism with Midazolam Levels in Critically Ill Children
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_gale_infotracacademiconefile_A745500672
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracacademiconefile_A745500672
Other Identifiers
ISSN
2075-4418
E-ISSN
2075-4418
DOI
10.3390/diagnostics12112797
