IClostridium botulinum/I C3 Toxin for Selective Delivery of Cargo into Dendritic Cells and Macrophag...
IClostridium botulinum/I C3 Toxin for Selective Delivery of Cargo into Dendritic Cells and Macrophages
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Publisher
MDPI AG
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Language
English
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Publisher
MDPI AG
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Contents
The protein toxin C3bot from Clostridium botulinum is a mono-ADP-ribosyltransferase that selectively intoxicates monocyte-derived cells such as macrophages, osteoclasts, and dendritic cells (DCs) by cytosolic modification of Rho-A, -B, and -C. Here, we investigated the application of C3bot as well as its non-toxic variant C3bot[sub.E174Q] as transp...
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Full title
IClostridium botulinum/I C3 Toxin for Selective Delivery of Cargo into Dendritic Cells and Macrophages
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TN_cdi_gale_infotracacademiconefile_A746716251
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracacademiconefile_A746716251
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ISSN
2072-6651
E-ISSN
2072-6651
DOI
10.3390/toxins14100711