γH2A/γH2AX Mediates DNA Damage-Specific Control of Checkpoint Signaling in ISaccharomyces cerevisiae...
γH2A/γH2AX Mediates DNA Damage-Specific Control of Checkpoint Signaling in ISaccharomyces cerevisiae/I
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Author / Creator
Siler, Jasmine , Guo, Na , Liu, Zhengfeng , Qin, Yuhua and Bi, Xin
Publisher
MDPI AG
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Language
English
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MDPI AG
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DNA lesions trigger DNA damage checkpoint (DDC) signaling which arrests cell cycle progression and promotes DNA damage repair. In Saccharomyces cerevisiae, phosphorylation of histone H2A (γH2A, equivalent to γH2AX in mammals) is an early chromatin mark induced by DNA damage that is recognized by a group of DDC and DNA repair factors. We find that γ...
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Full title
γH2A/γH2AX Mediates DNA Damage-Specific Control of Checkpoint Signaling in ISaccharomyces cerevisiae/I
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TN_cdi_gale_infotracacademiconefile_A786436719
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracacademiconefile_A786436719
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ISSN
1422-0067
DOI
10.3390/ijms25052462
