Viral infection induces inflammatory signals that coordinate YAP regulation of dysplastic cells in l...
Viral infection induces inflammatory signals that coordinate YAP regulation of dysplastic cells in lung alveoli
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Author / Creator
Lin, Xiuyu , Chen, Weicheng , Yang, Guilin , Zhang, Jiazhu , Wang, Huilin , Liu, Zeyu , Xi, Ying , Ren, Tao , Liu, Bo and Sui, Pengfei
Publisher
American Society for Clinical Investigation
Journal title
Language
English
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Publication information
Publisher
American Society for Clinical Investigation
Subjects
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Scope and Contents
Contents
Severe viral pneumonia can induce rapid expansion of [KRT5.sup.+] basal-like cells in small airways and alveoli; this forms a scar-like structure that persists in the injured alveoli and impedes normal alveolar epithelium regeneration. In this study, we investigated the mechanism by which viral infection induced this remodeling response. Through co...
Alternative Titles
Full title
Viral infection induces inflammatory signals that coordinate YAP regulation of dysplastic cells in lung alveoli
Authors, Artists and Contributors
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Record Identifier
TN_cdi_gale_infotracacademiconefile_A813643059
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracacademiconefile_A813643059
Other Identifiers
ISSN
0021-9738
DOI
10.1172/JCI176828.
