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ROR[gamma]t inverse agonists demonstrating a margin between inhibition of IL-17A and thymocyte apopt...

ROR[gamma]t inverse agonists demonstrating a margin between inhibition of IL-17A and thymocyte apopt...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracacademiconefile_A823804685

ROR[gamma]t inverse agonists demonstrating a margin between inhibition of IL-17A and thymocyte apoptosis

About this item

Full title

ROR[gamma]t inverse agonists demonstrating a margin between inhibition of IL-17A and thymocyte apoptosis

Publisher

Public Library of Science

Journal title

PloS one, 2025-01, Vol.20 (1), p.e0317090

Language

English

Formats

Publication information

Publisher

Public Library of Science

More information

Scope and Contents

Contents

Multiple genetic associations suggest a causative relationship between Th17-related genes coding for proteins, such as IL-17A, IL-23 and STAT3, and psoriasis. Further support for this link comes from the findings that neutralizing antibodies directed against IL-17A, IL-17RA and IL-23 are efficacious in diseases like psoriasis, psoriatic arthritis a...

Alternative Titles

Full title

ROR[gamma]t inverse agonists demonstrating a margin between inhibition of IL-17A and thymocyte apoptosis

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_gale_infotracacademiconefile_A823804685

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracacademiconefile_A823804685

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0317090

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