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Reduced in vivo phosphodiesterase-4 response to acute noradrenaline challenge in diet-induced obese...

Reduced in vivo phosphodiesterase-4 response to acute noradrenaline challenge in diet-induced obese...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotraccpiq_203898420

Reduced in vivo phosphodiesterase-4 response to acute noradrenaline challenge in diet-induced obese rats

About this item

Full title

Reduced in vivo phosphodiesterase-4 response to acute noradrenaline challenge in diet-induced obese rats

Publisher

Plattsburgh, NY: National Research Council of Canada

Journal title

Canadian journal of physiology and pharmacology, 2009-03, Vol.87 (3), p.196-202

Language

English

Formats

Publication information

Publisher

Plattsburgh, NY: National Research Council of Canada

More information

Scope and Contents

Contents

Altered sympathetic nervous activity has been linked to the development and persistence of obesity, partly relating to overfeeding. Binding of the selective, positron-emitting phosphodiesterase-4 (PDE4) inhibitor (R)-[
11
C]rolipram provides a direct index of the cAMP-hydrolyzing enzyme PDE4. This study examines progressive alterations in PDE...

Alternative Titles

Full title

Reduced in vivo phosphodiesterase-4 response to acute noradrenaline challenge in diet-induced obese rats

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_gale_infotraccpiq_203898420

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotraccpiq_203898420

Other Identifiers

ISSN

0008-4212

E-ISSN

1205-7541

DOI

10.1139/Y09-001

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