Synapse elimination and learning rules co-regulated by MHC class I H2-[D.sup.b]
Synapse elimination and learning rules co-regulated by MHC class I H2-[D.sup.b]
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Nature Publishing Group
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English
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Nature Publishing Group
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The formation of precise connections between retina and lateral geniculate nucleus (LGN) involves the activity- dependent elimination of some synapses, with strengthening and retention of others. Here we show that the major histocompatibility complex (MHC) class I molecule H2-[D.sup.b] is necessary and sufficient for synapse elimination in the reti...
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Synapse elimination and learning rules co-regulated by MHC class I H2-[D.sup.b]
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TN_cdi_gale_infotraccpiq_367642749
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotraccpiq_367642749
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ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/nature13154