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Synapse elimination and learning rules co-regulated by MHC class I H2-[D.sup.b]

Synapse elimination and learning rules co-regulated by MHC class I H2-[D.sup.b]

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotraccpiq_367642749

Synapse elimination and learning rules co-regulated by MHC class I H2-[D.sup.b]

About this item

Full title

Synapse elimination and learning rules co-regulated by MHC class I H2-[D.sup.b]

Publisher

Nature Publishing Group

Journal title

Nature (London), 2014-05, Vol.509 (7499), p.195

Language

English

Formats

Publication information

Publisher

Nature Publishing Group

More information

Scope and Contents

Contents

The formation of precise connections between retina and lateral geniculate nucleus (LGN) involves the activity- dependent elimination of some synapses, with strengthening and retention of others. Here we show that the major histocompatibility complex (MHC) class I molecule H2-[D.sup.b] is necessary and sufficient for synapse elimination in the reti...

Alternative Titles

Full title

Synapse elimination and learning rules co-regulated by MHC class I H2-[D.sup.b]

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_gale_infotraccpiq_367642749

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotraccpiq_367642749

Other Identifiers

ISSN

0028-0836

E-ISSN

1476-4687

DOI

10.1038/nature13154

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