The landscape of somatic mutation in normal colorectal epithelial cells
The landscape of somatic mutation in normal colorectal epithelial cells
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Full title
Author / Creator
Lee-Six, Henry , Olafsson, Sigurgeir , Ellis, Peter , Osborne, Robert J. , Sanders, Mathijs A. , Moore, Luiza , Georgakopoulos, Nikitas , Torrente, Franco , Noorani, Ayesha , Goddard, Martin , Robinson, Philip , Coorens, Tim H. H. , O’Neill, Laura , Alder, Christopher , Wang, Jingwei , Fitzgerald, Rebecca C. , Zilbauer, Matthias , Coleman, Nicholas , Saeb-Parsy, Kourosh , Martincorena, Inigo , Campbell, Peter J. and Stratton, Michael R.
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
The colorectal adenoma–carcinoma sequence has provided a paradigmatic framework for understanding the successive somatic genetic changes and consequent clonal expansions that lead to cancer
1
. However, our understanding of the earliest phases of colorectal neoplastic changes—which may occur in morphologically normal tissue—is comparatively l...
Alternative Titles
Full title
The landscape of somatic mutation in normal colorectal epithelial cells
Authors, Artists and Contributors
Author / Creator
Olafsson, Sigurgeir
Ellis, Peter
Osborne, Robert J.
Sanders, Mathijs A.
Moore, Luiza
Georgakopoulos, Nikitas
Torrente, Franco
Noorani, Ayesha
Goddard, Martin
Robinson, Philip
Coorens, Tim H. H.
O’Neill, Laura
Alder, Christopher
Wang, Jingwei
Fitzgerald, Rebecca C.
Zilbauer, Matthias
Coleman, Nicholas
Saeb-Parsy, Kourosh
Martincorena, Inigo
Campbell, Peter J.
Stratton, Michael R.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_gale_infotraccpiq_639118083
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotraccpiq_639118083
Other Identifiers
ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/s41586-019-1672-7