Targeted depletion of lymphotoxin-α-expressing [T.sub.H]1 and [T.sub.H]17 cells inhibits autoimmune...
Targeted depletion of lymphotoxin-α-expressing [T.sub.H]1 and [T.sub.H]17 cells inhibits autoimmune disease
About this item
Full title
Author / Creator
Chiang, Eugene Y , Kolumam, Ganesh A , Yu, Xin , Francesco, Michelle , Ivelja, Sinisa , Peng, Ivan , Gribling, Peter , Shu, Jean , Lee, Wyne P , Refino, Canio J , Balazs, Mercedesz , Paler-Martinez, Andres , Nguyen, Allen , Young, Judy , Barck, Kai H , Carano, Richard A.D , Ferrando, Ron , Diehl, Lauri , Chatterjea, Devavani and Grogan, Jane L
Publisher
Nature Publishing Group
Journal title
Language
English
Formats
Publication information
Publisher
Nature Publishing Group
Subjects
More information
Scope and Contents
Contents
Uncontrolled T helper type 1 ([T.sub.H]1) and [T.sub.H]17 cells are associated with autoimmune responses. We identify surface lymphotoxin-α (LT-α) as common to [T.sub.H]0, [T.sub.H]1 and [T.sub.H]17 cells and employ a unique strategy to target these subsets using a depleting monoclonal antibody (mAb) directed to surface LT-α. Depleting LT-α-specifi...
Alternative Titles
Full title
Targeted depletion of lymphotoxin-α-expressing [T.sub.H]1 and [T.sub.H]17 cells inhibits autoimmune disease
Authors, Artists and Contributors
Author / Creator
Kolumam, Ganesh A
Yu, Xin
Francesco, Michelle
Ivelja, Sinisa
Peng, Ivan
Gribling, Peter
Shu, Jean
Lee, Wyne P
Refino, Canio J
Balazs, Mercedesz
Paler-Martinez, Andres
Nguyen, Allen
Young, Judy
Barck, Kai H
Carano, Richard A.D
Ferrando, Ron
Diehl, Lauri
Chatterjea, Devavani
Grogan, Jane L
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_gale_infotracgeneralonefile_A203661057
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracgeneralonefile_A203661057
Other Identifiers
ISSN
1078-8956
