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ArticlesPeer ReviewedFull Text
Phosphorylation and linear ubiquitin direct A20 inhibition of inflammation
Author / Creator:Wertz, Ingrid E. ; Newton, Kim ; Seshasayee, Dhaya ; Kusam, Saritha ; Lam, Cynthia ; Zhang, Juan ; Popovych, Nataliya ; Helgason, Elizabeth ; Schoeffler, Allyn ; Jeet, Surinder ; Ramamoorthi, Nandhini ; Kategaya, Lorna ; Newman, Robert J. ; Horikawa, Keisuke ; Dugger, Debra ; Sandoval, Wendy ; Mukund, Susmith ; Zindal, Anuradha ; Martin, Flavius ; Quan, Clifford ; Tom, Jeffrey ; Fairbrother, Wayne J. ; Townsend, Michael ; Warming, Søren ; DeVoss, Jason ; Liu, Jinfeng ; Dueber, Erin ; Caplazi, Patrick ; Lee, Wyne P. ; Goodnow, Christopher C. ; Balazs, Mercedesz ; Yu, Kebing ; Kolumam, Ganesh ; Dixit, Vishva M.
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2015-12, Vol.528 (7582), p.370-375
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Loss of the Tumor Suppressor BAP1 Causes Myeloid Transformation
Author / Creator:Dey, Anwesha ; Seshasayee, Dhaya ; Noubade, Rajkumar ; French, Dorothy M. ; Liu, Jinfeng ; Chaurushiya, Mira S. ; Kirkpatrick, Donald S. ; Pham, Victoria C. ; Lill, Jennie R. ; Bakalarski, Corey E. ; Wu, Jiansheng ; Phu, Lilian ; Katavolos, Paula ; LaFave, Lindsay M. ; Abdel-Wahab, Omar ; Modrusan, Zora ; Seshagiri, Somasekar ; Dong, Ken ; Lin, Zhonghua ; Balazs, Mercedesz ; Suriben, Rowena ; Newton, Kim ; Hymowitz, Sarah ; Garcia-Manero, Guillermo ; Martin, Flavius ; Levine, Ross L. ; Dixit, Vishva M.
Publisher:Washington, DC: American Association for the Advancement of Science
Journal title:Science (American Association for the Advancement of Science), 2012-09, Vol.337 (6101), p.1541-1546
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Abrogation of growth hormone secretion rescues fatty liver in mice with hepatocyte-specific deletion of JAK2
Author / Creator:Sos, Brandon C. ; Harris, Charles ; Nordstrom, Sarah M. ; Tran, Jennifer L. ; Balázs, Mercedesz ; Caplazi, Patrick ; Febbraio, Maria ; Applegate, Milana A.B. ; Wagner, Kay-Uwe ; Weiss, Ethan J.
Publisher:United States: American Society for Clinical Investigation
Journal title:The Journal of clinical investigation, 2011-04, Vol.121 (4), p.1412-1423
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Equilibrative Nucleoside Transporter 3 Deficiency Perturbs Lysosome Function and Macrophage Homeostasis
Author / Creator:Hsu, Chia-Lin ; Lin, Weiyu ; Seshasayee, Dhaya ; Chen, Yung-Hsiang ; Ding, Xiao ; Lin, Zhonghua ; Suto, Eric ; Huang, Zhiyu ; Lee, Wyne P. ; Park, Hyunjoo ; Xu, Min ; Sun, Mei ; Rangell, Linda ; Lutman, Jeff L. ; Ulufatu, Sheila ; Stefanich, Eric ; Chalouni, Cecile ; Sagolla, Meredith ; Diehl, Lauri ; Fielder, Paul ; Dean, Brian ; Balazs, Mercedesz ; Martin, Flavius
Publisher:Washington, DC: American Association for the Advancement of Science
Journal title:Science (American Association for the Advancement of Science), 2012-01, Vol.335 (6064), p.89-92
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MRGPRX2 activation as a rapid, high-throughput mechanistic-based approach for detecting peptide-mediated human mast cell degranulation liabilities
Author / Creator:Lafleur, Marc A. ; Werner, Jonathan ; Fort, Madeline ; Lobenhofer, Edward K. ; Balazs, Mercedesz ; Goyos, Ana
Publisher:Abingdon: Taylor & Francis
Journal title:Journal of immunotoxicology, 2020-01, Vol.17 (1), p.110-121
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Antibodies specific for a segment of human membrane IgE deplete IgE-producing B cells in humanized mice
Author / Creator:Brightbill, Hans D. ; Jeet, Surinder ; Lin, Zhonghua ; Yan, Donghong ; Zhou, Meijuan ; Tan, Martha ; Nguyen, Allen ; Yeh, Sherry ; Delarosa, Donnie ; Leong, Steven R. ; Wong, Terence ; Chen, Yvonne ; Ultsch, Mark ; Luis, Elizabeth ; Ramani, Sree Ranjani ; Jackman, Janet ; Gonzalez, Lino ; Dennis, Mark S. ; Chuntharapai, Anan ; DeForge, Laura ; Meng, Y. Gloria ; Xu, Min ; Eigenbrot, Charles ; Lee, Wyne P. ; Refino, Canio J. ; Balazs, Mercedesz ; Wu, Lawren C.
Publisher:United States: American Society for Clinical Investigation
Journal title:The Journal of clinical investigation, 2010-06, Vol.120 (6), p.2218-2229
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In Vivo Depletion of Lymphotoxin-Alpha Expressing Lymphocytes Inhibits Xenogeneic Graft-versus-Host-Disease
Author / Creator:Chiang, Eugene Y. ; Kolumam, Ganesh ; McCutcheon, Krista M. ; Young, Judy ; Lin, Zhonghua ; Balazs, Mercedesz ; Grogan, Jane L.
Publisher:United States: Public Library of Science
Journal title:PloS one, 2012-03, Vol.7 (3), p.e33106
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Polyclonal hyper-IgE mouse model reveals mechanistic insights into antibody class switch recombination
Author / Creator:Misaghi, Shahram ; Senger, Kate ; Sai, Tao ; Qu, Yan ; Sun, Yonglian ; Hamidzadeh, Kajal ; Nguyen, Allen ; Jin, Zhaoyu ; Zhou, Meijuan ; Yan, Donghong ; Lin, Wei Yu ; Lin, Zhonghua ; Lorenzo, Maria N. ; Sebrell, Andrew ; Ding, Jiabing ; Xu, Min ; Caplazi, Patrick ; Austin, Cary D. ; Balazs, Mercedesz ; Roose-Girma, Merone ; DeForge, Laura ; Warming, Søren ; Lee, Wyne P. ; Dixit, Vishva M. ; Zarrin, Ali A.
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2013-09, Vol.110 (39), p.15770-15775
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ArticlesPeer ReviewedFull Text
Abrogation of growth hormone secretion rescues fatty liver in mice with hepatocyte-specific deletion of JAK2
Author / Creator:Sos, Brandon C. ; Harris, Charles ; Nordstrom, Sarah M. ; Tran, Jennifer L. ; Balázs, Mercedesz ; Caplazi, Patrick ; Febbraio, Maria ; Applegate, Milana A.B. ; Wagner, Kay-Uwe ; Weiss, Ethan J.
Publisher:American Society for Clinical Investigation
Journal title:The Journal of clinical investigation, 2011-08, Vol.121 (8), p.3360-3360
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Distinct roles of lymphotoxin-β signaling and the homeodomain transcription factor Nkx2.3 in the ontogeny of endothelial compartments in spleen
Author / Creator:Balogh, Péter ; Balázs, Mercedesz ; Czömpöly, Tamás ; Weih, Debra S. ; Arnold, Hans-Henning ; Weih, Falk
Publisher:Germany
Journal title:Cell and tissue research, 2007-06, Vol.328 (3), p.473-486
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IL-17C regulates the innate immune function of epithelial cells in an autocrine manner
Author / Creator:Ramirez-Carrozzi, Vladimir ; Sambandam, Arivazhagan ; Luis, Elizabeth ; Lin, Zhongua ; Jeet, Surinder ; Lesch, Justin ; Hackney, Jason ; Kim, Janice ; Zhou, Meijuan ; Lai, Joyce ; Modrusan, Zora ; Sai, Tao ; Lee, Wyne ; Xu, Min ; Caplazi, Patrick ; Diehl, Lauri ; de Voss, Jason ; Balazs, Mercedesz ; Gonzalez, Lino ; Singh, Harinder ; Ouyang, Wenjun ; Pappu, Rajita
Publisher:New York: Nature Publishing Group US
Journal title:Nature immunology, 2011-12, Vol.12 (12), p.1159-1166
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Specific Btk inhibition suppresses B cell– and myeloid cell–mediated arthritis
Author / Creator:Di Paolo, Julie A ; Huang, Tao ; Balazs, Mercedesz ; Barbosa, James ; Barck, Kai H ; Bravo, Brandon J ; Carano, Richard A D ; Darrow, James ; Davies, Douglas R ; DeForge, Laura E ; Diehl, Lauri ; Ferrando, Ronald ; Gallion, Steven L ; Giannetti, Anthony M ; Gribling, Peter ; Hurez, Vincent ; Hymowitz, Sarah G ; Jones, Randall ; Kropf, Jeffrey E ; Lee, Wyne P ; Maciejewski, Patricia M ; Mitchell, Scott A ; Rong, Hong ; Staker, Bart L ; Whitney, J Andrew ; Yeh, Sherry ; Young, Wendy B ; Yu, Christine ; Zhang, Juan ; Reif, Karin ; Currie, Kevin S
Publisher:New York: Nature Publishing Group US
Journal title:Nature chemical biology, 2011-01, Vol.7 (1), p.41-50
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In vivo antigen-driven plasmablast enrichment in combination with antigen-specific cell sorting to facilitate the isolation of rare monoclonal antibodies from human B cells
Author / Creator:Lin, Zhonghua ; Chiang, Nancy Y ; Chai, Ning ; Seshasayee, Dhaya ; Lee, Wyne P ; Balazs, Mercedesz ; Nakamura, Gerald ; Swem, Lee R
Publisher:London: Nature Publishing Group UK
Journal title:Nature protocols, 2014-07, Vol.9 (7), p.1563-1577
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Erratum: Phosphorylation and linear ubiquitin direct A20 inhibition of inflammation
Author / Creator:Wertz, Ingrid E. ; Newton, Kim ; Seshasayee, Dhaya ; Kusam, Saritha ; Lam, Cynthia ; Zhang, Juan ; Popovych, Nataliya ; Helgason, Elizabeth ; Schoeffler, Allyn ; Jeet, Surinder ; Ramamoorthi, Nandhini ; Kategaya, Lorna ; Newman, Robert J. ; Horikawa, Keisuke ; Dugger, Debra ; Sandoval, Wendy ; Mukund, Susmith ; Zindal, Anuradha ; Martin, Flavius ; Quan, Clifford ; Tom, Jeffrey ; Fairbrother, Wayne J. ; Townsend, Michael ; Warming, Søren ; DeVoss, Jason ; Liu, Jinfeng ; Dueber, Erin ; Caplazi, Patrick ; Lee, Wyne P. ; Goodnow, Christopher C. ; Balazs, Mercedesz ; Yu, Kebing ; Kolumam, Ganesh ; Dixit, Vishva M.
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2016-04, Vol.532 (7599), p.402-402
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Targeted depletion of lymphotoxin- alpha -expressing T sub(H)1 and T sub(H)17 cells inhibits autoimmune disease
Author / Creator:Chiang, Eugene Y ; Kolumam, Ganesh A ; Yu, Xin ; Francesco, Michelle ; Ivelja, Sinisa ; Peng, Ivan ; Gribling, Peter ; Shu, Jean ; Lee, Wyne P ; Refino, Canio J ; Balazs, Mercedesz ; Paler-Martinez, Andres ; Nguyen, Allen ; Young, Judy ; Barck, Kai H ; Carano, Richard A D ; Ferrando, Ron ; Diehl, Lauri ; Chatterjea, Devavani ; Grogan, Jane L
Journal title:Nature medicine, 2009-07, Vol.15 (7), p.766-773
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Targeted depletion of lymphotoxin-α-expressing [T.sub.H]1 and [T.sub.H]17 cells inhibits autoimmune disease
Author / Creator:Chiang, Eugene Y ; Kolumam, Ganesh A ; Yu, Xin ; Francesco, Michelle ; Ivelja, Sinisa ; Peng, Ivan ; Gribling, Peter ; Shu, Jean ; Lee, Wyne P ; Refino, Canio J ; Balazs, Mercedesz ; Paler-Martinez, Andres ; Nguyen, Allen ; Young, Judy ; Barck, Kai H ; Carano, Richard A.D ; Ferrando, Ron ; Diehl, Lauri ; Chatterjea, Devavani ; Grogan, Jane L
Publisher:Nature Publishing Group
Journal title:Nature medicine, 2009-07, Vol.15 (7), p.766
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Targeted depletion of lymphotoxin-α–expressing TH1 and TH17 cells inhibits autoimmune disease
Author / Creator:Chiang, Eugene Y ; Kolumam, Ganesh A ; Yu, Xin ; Francesco, Michelle ; Ivelja, Sinisa ; Peng, Ivan ; Gribling, Peter ; Shu, Jean ; Lee, Wyne P ; Refino, Canio J ; Balazs, Mercedesz ; Paler-Martinez, Andres ; Nguyen, Allen ; Young, Judy ; Barck, Kai H ; Carano, Richard A D ; Ferrando, Ron ; Diehl, Lauri ; Chatterjea, Devavani ; Grogan, Jane L
Publisher:New York: Nature Publishing Group US
Journal title:Nature medicine, 2009-07, Vol.15 (7), p.766-773
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Targeted depletion of lymphotoxin-[alpha]-expressing TH1 and TH17 cells inhibits autoimmune disease
Author / Creator:Chiang, Eugene Y ; Kolumam, Ganesh A ; Yu, Xin ; Francesco, Michelle ; Ivelja, Sinisa ; Peng, Ivan ; Gribling, Peter ; Shu, Jean ; Lee, Wyne P ; Refino, Canio J ; Balazs, Mercedesz ; Paler-martinez, Andres ; Nguyen, Allen ; Young, Judy ; Barck, Kai H ; Carano, Richard A D ; Ferrando, Ron ; Diehl, Lauri ; Chatterjea, Devavani ; Grogan, Jane L
Publisher:New York: Nature Publishing Group
Journal title:Nature medicine, 2009-07, Vol.15 (7), p.766
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Distinct roles of lymphotoxin-[beta] signaling and the homeodomain transcription factor Nkx2.3 in the ontogeny of endothelial compartments in spleen
Author / Creator:Balogh, Péter ; Mercedesz Balázs ; Czömpöly, Tamás ; Weih, Debra S ; Hans-Henning, Arnold ; Weih, Falk
Publisher:Heidelberg: Springer Nature B.V
Journal title:Cell and tissue research, 2007-06, Vol.328 (3), p.473
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Phosphorylation and linear ubiquitin direct A20 inhibition of inflammation

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Loss of the Tumor Suppressor BAP1 Causes Myeloid Transformation

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Abrogation of growth hormone secretion rescues fatty liver in mice with hepatocyte-specific deletion of JAK2

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Equilibrative Nucleoside Transporter 3 Deficiency Perturbs Lysosome Function and Macrophage Homeostasis

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MRGPRX2 activation as a rapid, high-throughput mechanistic-based approach for detecting peptide-mediated human mast cell degranulation liabilities

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Antibodies specific for a segment of human membrane IgE deplete IgE-producing B cells in humanized mice

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In Vivo Depletion of Lymphotoxin-Alpha Expressing Lymphocytes Inhibits Xenogeneic Graft-versus-Host-Disease

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Polyclonal hyper-IgE mouse model reveals mechanistic insights into antibody class switch recombination

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Abrogation of growth hormone secretion rescues fatty liver in mice with hepatocyte-specific deletion of JAK2

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Distinct roles of lymphotoxin-β signaling and the homeodomain transcription factor Nkx2.3 in the ontogeny of endothelial compartments in spleen

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IL-17C regulates the innate immune function of epithelial cells in an autocrine manner

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Specific Btk inhibition suppresses B cell– and myeloid cell–mediated arthritis

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In vivo antigen-driven plasmablast enrichment in combination with antigen-specific cell sorting to facilitate the isolation of rare monoclonal antibodies from human B cells

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Erratum: Phosphorylation and linear ubiquitin direct A20 inhibition of inflammation

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Targeted depletion of lymphotoxin- alpha -expressing T sub(H)1 and T sub(H)17 cells inhibits autoimmune disease

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Targeted depletion of lymphotoxin-α-expressing [T.sub.H]1 and [T.sub.H]17 cells inhibits autoimmune disease

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Targeted depletion of lymphotoxin-α–expressing TH1 and TH17 cells inhibits autoimmune disease

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Targeted depletion of lymphotoxin-[alpha]-expressing TH1 and TH17 cells inhibits autoimmune disease

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Distinct roles of lymphotoxin-[beta] signaling and the homeodomain transcription factor Nkx2.3 in the ontogeny of endothelial compartments in spleen

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