Hypoxia acts through multiple signaling pathways to induce metallothionein transactivation by the me...
Hypoxia acts through multiple signaling pathways to induce metallothionein transactivation by the metal-responsive transcription factor-1
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Publisher
NRC Research Press
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Language
English
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NRC Research Press
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Contents
Metal-responsive transcription factor-1 (MTF-1) is essential for the induction of genes encoding metallothionein by metals and hypoxia. Here, we studied the mechanism controlling the activation of MTF-1 by hypoxia. Hypoxia activation of Mt gene transcription is dependent on the presence of metal regulatory elements (MREs) in the promoter of Mt gene...
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Full title
Hypoxia acts through multiple signaling pathways to induce metallothionein transactivation by the metal-responsive transcription factor-1
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TN_cdi_gale_infotracgeneralonefile_A275312563
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracgeneralonefile_A275312563
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ISSN
0829-8211
DOI
10.1139/O11-063
