Direct arylation of strong aliphatic C-H bonds
Direct arylation of strong aliphatic C-H bonds
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Nature Publishing Group
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English
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Nature Publishing Group
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Despite the widespread success of transition-metal-catalysed cross-coupling methodologies, considerable limitations still exist in reactions at sp.sup.3-hybridized carbon atoms, with most approaches relying on prefunctionalized alkylmetal or bromide coupling partners.sup.1,2. Although the use of native functional groups (for example, carboxylic aci...
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Direct arylation of strong aliphatic C-H bonds
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TN_cdi_gale_infotracgeneralonefile_A572748350
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracgeneralonefile_A572748350
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ISSN
0028-0836
DOI
10.1038/s41586-018-0366-x