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Phase separation organizes the site of autophagosome formation

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Phase separation organizes the site of autophagosome formation

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracgeneralonefile_A660675779

Phase separation organizes the site of autophagosome formation

About this item

Full title

Phase separation organizes the site of autophagosome formation

Author / Creator

Fujioka, Yuko , Alam, Jahangir Md , Noshiro, Daisuke , Mouri, Kazunari , Ando, Toshio , Okada, Yasushi , May, Alexander I , Knorr, Roland L , Suzuki, Kuninori , Ohsumi, Yoshinori and Noda, Nobuo N

Publisher

Nature Publishing Group

Journal title

Nature, 2020, Vol.578 (7794), p.301

Language

English

Formats

Reports

Publication information

Publisher

Nature Publishing Group

Subjects

More information

Scope and Contents

Contents

Many biomolecules undergo liquid-liquid phase separation to form liquid-like condensates that mediate diverse cellular functions.sup.1,2. Autophagy is able to degrade such condensates using autophagosomes--double-membrane structures that are synthesized de novo at the pre-autophagosomal structure (PAS) in yeast.sup.3-5. Whereas Atg proteins that as...

Alternative Titles

Full title

Phase separation organizes the site of autophagosome formation

Authors, Artists and Contributors

Author / Creator

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_gale_infotracgeneralonefile_A660675779

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracgeneralonefile_A660675779

Other Identifiers

ISSN

0028-0836

DOI

10.1038/s41586-020-1977-6

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