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Heteroarylketones inhibit astroglial interleukin-6 expression via a STAT3/NF-[kappa]B signaling path...

Heteroarylketones inhibit astroglial interleukin-6 expression via a STAT3/NF-[kappa]B signaling path...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A265233306

Heteroarylketones inhibit astroglial interleukin-6 expression via a STAT3/NF-[kappa]B signaling pathway

About this item

Full title

Heteroarylketones inhibit astroglial interleukin-6 expression via a STAT3/NF-[kappa]B signaling pathway

Publisher

BioMed Central Ltd

Journal title

Journal of neuroinflammation, 2011-07, Vol.8, p.86

Language

English

Formats

Publication information

Publisher

BioMed Central Ltd

More information

Scope and Contents

Contents

Background Elevated brain levels of the pleiotropic cytokine interleukin-6, which is mainly secreted from activated local astrocytes, contribute to pathological events including neuroinflammation and neurodegeneration. Thus, inhibition of pathological IL-6 expression provides a rationale strategy for targeting the onset or further progression of ne...

Alternative Titles

Full title

Heteroarylketones inhibit astroglial interleukin-6 expression via a STAT3/NF-[kappa]B signaling pathway

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_gale_infotracmisc_A265233306

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A265233306

Other Identifiers

ISSN

1742-2094

E-ISSN

1742-2094

DOI

10.1186/1742-2094-8-86

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