RUNX1 mutations in acute myeloid leukemia are associated with distinct clinico-pathologic and geneti...
RUNX1 mutations in acute myeloid leukemia are associated with distinct clinico-pathologic and genetic features
About this item
Full title
Author / Creator
Gaidzik, V I , Teleanu, V , Papaemmanuil, E , Weber, D , Paschka, P , Hahn, J , Wallrabenstein, T , Kolbinger, B , Köhne, C H , Horst, H A , Brossart, P , Held, G , Kündgen, A , Ringhoffer, M , Götze, K , Rummel, M , Gerstung, M , Campbell, P , Kraus, J M , Kestler, H A , Thol, F , Heuser, M , Schlegelberger, B , Ganser, A , Bullinger, L , Schlenk, R F , Döhner, K and Döhner, H
Publisher
Nature Publishing Group
Journal title
Language
English
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Publication information
Publisher
Nature Publishing Group
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More information
Scope and Contents
Contents
We evaluated the frequency, genetic architecture, clinico-pathologic features and prognostic impact of RUNX1 mutations in 2439 adult patients with newly-diagnosed acute myeloid leukemia (AML). RUNX1 mutations were found in 245 of 2439 (10%) patients; were almost mutually exclusive of AML with recurrent genetic abnormalities; and they co-occurred wi...
Alternative Titles
Full title
RUNX1 mutations in acute myeloid leukemia are associated with distinct clinico-pathologic and genetic features
Authors, Artists and Contributors
Author / Creator
Teleanu, V
Papaemmanuil, E
Weber, D
Paschka, P
Hahn, J
Wallrabenstein, T
Kolbinger, B
Köhne, C H
Horst, H A
Brossart, P
Held, G
Kündgen, A
Ringhoffer, M
Götze, K
Rummel, M
Gerstung, M
Campbell, P
Kraus, J M
Kestler, H A
Thol, F
Heuser, M
Schlegelberger, B
Ganser, A
Bullinger, L
Schlenk, R F
Döhner, K
Döhner, H
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_gale_infotracmisc_A468616398
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A468616398
Other Identifiers
ISSN
0887-6924
DOI
10.1038/leu.2016.126
