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Synergy between trastuzumab and pertuzumab for human epidermal growth factor 2 (Her2) from colocaliz...

Synergy between trastuzumab and pertuzumab for human epidermal growth factor 2 (Her2) from colocaliz...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A478424651

Synergy between trastuzumab and pertuzumab for human epidermal growth factor 2 (Her2) from colocalization: an in silicobased mechanism

About this item

Full title

Synergy between trastuzumab and pertuzumab for human epidermal growth factor 2 (Her2) from colocalization: an in silicobased mechanism

Publisher

BioMed Central Ltd

Journal title

Breast cancer research : BCR, 2011-05, Vol.13 (3), Article R54

Language

English

Formats

Publication information

Publisher

BioMed Central Ltd

More information

Scope and Contents

Contents

Introduction Human epidermal growth factor 2 (Her2), a receptor tyrosine kinase, is overexpressed in breast cancers. It has been successfully targeted by small molecule kinase inhibitors and by antibodies. Recent clinical data show a synergistic response in patients when two antibodies, trastuzumab and pertuzumab, are given in combination. Methods...

Alternative Titles

Full title

Synergy between trastuzumab and pertuzumab for human epidermal growth factor 2 (Her2) from colocalization: an in silicobased mechanism

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_gale_infotracmisc_A478424651

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A478424651

Other Identifiers

ISSN

1465-542X,1465-5411

E-ISSN

1465-542X

DOI

10.1186/bcr2888

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