Niemann-Pick type C proteins promote microautophagy by expanding raft-like membrane domains in the y...
Niemann-Pick type C proteins promote microautophagy by expanding raft-like membrane domains in the yeast vacuole
About this item
Full title
Author / Creator
Publisher
eLife Science Publications, Ltd
Journal title
Language
English
Formats
Publication information
Publisher
eLife Science Publications, Ltd
Subjects
More information
Scope and Contents
Contents
Niemann-Pick type C is a storage disease caused by dysfunction of NPC proteins, which transport cholesterol from the lumen of lysosomes to the limiting membrane of that compartment. Using freeze fracture electron microscopy, we show here that the yeast NPC orthologs, Ncr1p and Npc2p, are essential for formation and expansion of raft-like domains in...
Alternative Titles
Full title
Niemann-Pick type C proteins promote microautophagy by expanding raft-like membrane domains in the yeast vacuole
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_gale_infotracmisc_A494662770
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A494662770
Other Identifiers
ISSN
2050-084X
E-ISSN
2050-084X
DOI
10.7554/eLife.25960
