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A newly developed oxime K203 is the most effective reactivator of tabun-inhibited acetylcholinestera...

A newly developed oxime K203 is the most effective reactivator of tabun-inhibited acetylcholinestera...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A528510049

A newly developed oxime K203 is the most effective reactivator of tabun-inhibited acetylcholinesterase

About this item

Full title

A newly developed oxime K203 is the most effective reactivator of tabun-inhibited acetylcholinesterase

Publisher

BioMed Central Ltd

Journal title

BMC Pharmacology and Toxicology, 2018, Vol.19 (1)

Language

English

Formats

Publication information

Publisher

BioMed Central Ltd

More information

Scope and Contents

Contents

Based on in vitro and in vivo rat experiments, the newly developed acetylcholinesterase (AChE) reactivator, K203, appears to be much more effective in the treatment of tabun poisonings than currently fielded oximes. To determine if this reactivating efficacy would extend to humans, studies were conducted in vitro using human brain homogenate as the...

Alternative Titles

Full title

A newly developed oxime K203 is the most effective reactivator of tabun-inhibited acetylcholinesterase

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_gale_infotracmisc_A528510049

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A528510049

Other Identifiers

ISSN

2050-6511

E-ISSN

2050-6511

DOI

10.1186/s40360-018-0196-3

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