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Protein kinase C-delta regulates HIV-1 replication at an early post-entry step in macrophages

Protein kinase C-delta regulates HIV-1 replication at an early post-entry step in macrophages

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A534287829

Protein kinase C-delta regulates HIV-1 replication at an early post-entry step in macrophages

About this item

Full title

Protein kinase C-delta regulates HIV-1 replication at an early post-entry step in macrophages

Publisher

BioMed Central Ltd

Journal title

Retrovirology, 2012, Vol.9

Language

English

Formats

Publication information

Publisher

BioMed Central Ltd

More information

Scope and Contents

Contents

Macrophages, which are CD4 and CCR5 positive, can sustain HIV-1 replication for long periods of time. Thus, these cells play critical roles in the transmission, dissemination and persistence of viral infection. Of note, current antiviral therapies do not target macrophages efficiently. Previously, it was demonstrated that interactions between CCR5...

Alternative Titles

Full title

Protein kinase C-delta regulates HIV-1 replication at an early post-entry step in macrophages

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_gale_infotracmisc_A534287829

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A534287829

Other Identifiers

ISSN

1742-4690

E-ISSN

1742-4690

DOI

10.1186/1742-4690-9-37

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