Efficient cellular fractionation improves RNA sequencing analysis of mature and nascent transcripts...
Efficient cellular fractionation improves RNA sequencing analysis of mature and nascent transcripts from human tissues
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Publisher
BioMed Central Ltd
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Language
English
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Publisher
BioMed Central Ltd
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Contents
The starting material for RNA sequencing (RNA-seq) studies is usually total RNA or polyA+ RNA. Both forms of RNA represent heterogeneous pools of RNA molecules at different levels of maturation and processing. Such heterogeneity, in addition to the biases associated with polyA+ purification steps, may influence the analysis, sensitivity and the int...
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Full title
Efficient cellular fractionation improves RNA sequencing analysis of mature and nascent transcripts from human tissues
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TN_cdi_gale_infotracmisc_A534630859
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A534630859
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ISSN
1472-6750
E-ISSN
1472-6750
DOI
10.1186/1472-6750-13-99
