Comparative analysis of single and combined APP/APLP knockouts reveals reduced spine density in APP-...
Comparative analysis of single and combined APP/APLP knockouts reveals reduced spine density in APP-KO mice that is prevented by APPs[alpha] expression
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BioMed Central Ltd
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English
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BioMed Central Ltd
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Synaptic dysfunction and synapse loss are key features of Alzheimer's pathogenesis. Previously, we showed an essential function of APP and APLP2 for synaptic plasticity, learning and memory. Here, we used organotypic hippocampal cultures to investigate the specific role(s) of APP family members and their fragments for dendritic complexity and spine...
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Comparative analysis of single and combined APP/APLP knockouts reveals reduced spine density in APP-KO mice that is prevented by APPs[alpha] expression
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TN_cdi_gale_infotracmisc_A541270111
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A541270111
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ISSN
2051-5960
E-ISSN
2051-5960
DOI
10.1186/2051-5960-2-36
