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Preclinical characterization of the JAK/STAT inhibitor SGI-1252 on skeletal muscle function, morphol...

Preclinical characterization of the JAK/STAT inhibitor SGI-1252 on skeletal muscle function, morphol...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A543294220

Preclinical characterization of the JAK/STAT inhibitor SGI-1252 on skeletal muscle function, morphology and satellite cell content

About this item

Full title

Preclinical characterization of the JAK/STAT inhibitor SGI-1252 on skeletal muscle function, morphology and satellite cell content

Publisher

Public Library of Science

Journal title

PLoS ONE, 2018, Vol.13 (6), p.e0198611

Language

English

Formats

Publication information

Publisher

Public Library of Science

More information

Scope and Contents

Contents

Recent studies have highlighted the JAK/STAT signaling pathway in the regulation of muscle satellite cell behavior. Herein we report preclinical studies designed to characterize the effects of a novel JAK/STAT inhibitor on plantar flexor skeletal muscle function, morphology, and satellite cell content. The compound, SGI-1252, was administered orall...

Alternative Titles

Full title

Preclinical characterization of the JAK/STAT inhibitor SGI-1252 on skeletal muscle function, morphology and satellite cell content

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_gale_infotracmisc_A543294220

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A543294220

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0198611

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