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Potent prion-like behaviors of pathogenic [alpha]-synuclein and evaluation of inactivation methods

Potent prion-like behaviors of pathogenic [alpha]-synuclein and evaluation of inactivation methods

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A546834881

Potent prion-like behaviors of pathogenic [alpha]-synuclein and evaluation of inactivation methods

About this item

Full title

Potent prion-like behaviors of pathogenic [alpha]-synuclein and evaluation of inactivation methods

Publisher

BioMed Central Ltd

Journal title

Acta neuropathologica communications, 2018-04, Vol.6 (1)

Language

English

Formats

Publication information

Publisher

BioMed Central Ltd

More information

Scope and Contents

Contents

The concept that abnormal protein aggregates show prion-like propagation between cells has been considered to explain the onset and progression of many neurodegenerative diseases. Indeed, both synthetic amyloid-like fibrils and pathogenic proteins extracted from patients' brains induce self-templated amplification and cell-to-cell transmission in v...

Alternative Titles

Full title

Potent prion-like behaviors of pathogenic [alpha]-synuclein and evaluation of inactivation methods

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_gale_infotracmisc_A546834881

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A546834881

Other Identifiers

ISSN

2051-5960

E-ISSN

2051-5960

DOI

10.1186/s40478-018-0532-2

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