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Evidence of intraneuronal A[beta] accumulation preceding tau pathology in the entorhinal cortex

Evidence of intraneuronal A[beta] accumulation preceding tau pathology in the entorhinal cortex

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A566622713

Evidence of intraneuronal A[beta] accumulation preceding tau pathology in the entorhinal cortex

About this item

Full title

Evidence of intraneuronal A[beta] accumulation preceding tau pathology in the entorhinal cortex

Publisher

Springer

Journal title

Acta neuropathologica, 2018-12, Vol.136 (6), p.901

Language

English

Formats

Publication information

Publisher

Springer

More information

Scope and Contents

Contents

Growing evidence gathered from transgenic animal models of Alzheimer's disease (AD) indicates that the intraneuronal accumulation of amyloid-[beta] (A[beta]) peptides is an early event in the AD pathogenesis, producing cognitive deficits before the deposition of insoluble plaques. Levels of soluble A[beta] are also a strong indicator of synaptic de...

Alternative Titles

Full title

Evidence of intraneuronal A[beta] accumulation preceding tau pathology in the entorhinal cortex

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_gale_infotracmisc_A566622713

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A566622713

Other Identifiers

ISSN

0001-6322

DOI

10.1007/s00401-018-1922-z

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